Dr. Yoon is honored with election into ASCI

   

Category Archives: Journal Club

2013-06-28 Journal Club (Sang-Ho Lee) Li W et al., 2013 Dev Cell

Dev Cell. 2013 Feb 25;24(4):359-71. doi: 10.1016/j.devcel.2013.01.009. Epub 2013 Feb 7. Peripheral nerve-derived CXCL12 and VEGF-A regulate the patterning of arterial vessel branching in developing limb skin. Li W, Kohara H, Uchida Y, James JM, Soneji K, Cronshaw DG, Zou YR, Nagasawa T, Mukouyama YS. Source Laboratory of Stem Cell and Neuro-Vascular Biology, Genetics and Developmental Biology Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Building […]

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4/22/13 Journal Club, Jaeyeaon Cho; Nam et al., PNAS, 2013

Proc Natl Acad Sci U S A. 2013 Apr 2;110(14):5588-93. doi: 10.1073/pnas.1301019110. Epub 2013 Mar 4.   Reprogramming of human fibroblasts toward a cardiac fate. Nam YJ, Song K, Luo X, Daniel E, Lambeth K, West K, Hill JA, Dimaio JM, Baker LA, Bassel-Duby R, Olson EN. Departments of Molecular Biology, Internal Medicine, Cardiothoracic Surgery, and Urology, and Center for Human Genetics/McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center, Dallas, TX 75390. […]

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4/8/13 Journal Club, Kyuwon Cho, Boon et al., Nature, 2013

Ageing is the predominant risk factor for cardiovascular diseases and contributes to a significantly worse outcome in patients with acute myocardial infarction. MicroRNAs (miRNAs) have emerged as crucial regulators of cardiovascular function and some miRNAs have key roles in ageing. We propose that altered expression of miRNAs in the heart during ageing contributes to the age-dependent decline in cardiac function. Here we show that miR-34a is induced in the ageing heart and that in vivo silencing or genetic deletion of miR-34a reduces age-associated cardiomyocyte cell death. Moreover, miR-34a inhibition

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