Yoon Lab – Stem Cell Research Group

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2nd Cardiovascular Reprogramming
and Regeneration Conference 2026

Join leading scientists, clinicians, and innovators at the 2nd CRR Conference 2026 in Boston on July 11, 2026, as we explore the latest advances in cardiomyocyte reprogramming, vascular regeneration, cardiac organoids, and bioengineering. This one-day event will feature distinguished speakers, interactive scientific sessions, and valuable networking opportunities in cardiovascular regenerative medicine.

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Diverse Stem Cell Applications

Our research delves into the use of both pluripotent and adult stem cells for heart and vascular regeneration. We focus on pluripotent cells like induced pluripotent and embryonic stem cells for their adaptability. Simultaneously, we tap into the potential of adult stem cells, including endothelial, mesenchymal, and bone marrow-derived multipotent stem cells, along with CD31+ and hematopoietic stem cells, for their targeted repair capabilities.

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Cardiovascular Disease Intervention

Our efforts are directed towards tackling key cardiovascular diseases, including myocardial infarction, chronic heart failure, peripheral vascular diseases like peripheral arterial occlusive disease, diabetic neuropathy, lymphedema, and wound healing. By understanding and addressing these conditions, we aim to bring forward new therapeutic approaches and improve patient outcomes.

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In Vitro Differentiation Innovation

We are at the forefront of innovating with in vitro differentiation of pluripotent stem cells. Our focus is on transforming these cells into endothelial cells, cardiomyocytes, and lymphatic vessels, exploring their potential in effectively treating targeted cardiovascular diseases. This approach opens new avenues for understanding disease mechanisms and developing tailored therapies.

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Biomaterial-Enhanced Stem Cell Therapy

A pioneering aspect of our research involves integrating biomaterial technologies with stem cell applications. This synergy enhances cardiac repair, offering a novel approach to healing heart tissue. Through this integration, we aim to improve the efficacy and durability of stem cell therapies in cardiac regeneration, marking a significant advancement in cardiac care.

Research Team

Dr. Young-sup Yoon

Areas of Research

Highlighted Publications

The Yoon Lab Stem Cell Research Group has an impressive track record, with over 100 publications in top-tier journals like Nature Medicine, JCI, Circulation, and others. Dr. Yoon’s research excellence has been recognized through numerous awards, including being a finalist for the AHA and ACC Young Investigator Awards.

As a Fellow of the American Heart Association and a chartered member of the NIH study section, Dr. Yoon plays a pivotal role in cardiovascular science. He also contributes as an editorial board member for journals like Circulation Research and PLOS One.

His achievements extend to accolades from Emory University, including the Faculty Excellence Award in 2014 and the Innovation of 2012 Award. Notably, he was the first Korean medical school graduate elected to the American Society for Clinical Investigation, highlighting his significant impact in medical research.

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The Mission of Yoon Lab

Our expertise lies in the generation and manipulation of various stem and progenitor cells, including induced pluripotent stem cells, multipotent bone marrow cells, and angio-vasculogenic cells. By harnessing the potential of these cells, we aim to create effective therapies for a range of cardiovascular conditions. Our primary focus is on differentiating these cells into specialized types, such as endothelial cells and cardiomyocytes, to repair and regenerate damaged heart and blood vessels.

Our research is particularly relevant in addressing peripheral vascular disease and its complications in diabetes, myocardial infarction, lymphedema, and diabetic neuropathy. By delving deep into the mechanistic aspects of these diseases, we strive to understand and enhance the therapeutic utility of our cellular and tissue engineering approaches.

At Yoon Lab, we are committed to advancing the frontiers of medicine through our dedicated research, innovative strategies, and the relentless pursuit of knowledge to improve patient outcomes in cardiovascular diseases. Join us in our journey towards a healthier, heartier future.

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About Us

NIH/DP3&R01

Grants Received

100+

Journal Articles

2008

Found Since

150+

Lab Alumni

13+

Affiliations

News and Updates

**Emory’s 31st Annual Cardiology Research Symposium**

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Regenerative Medicine at Emory University

Researchers in Emory University’s new regenerative medicine program are working to develop new therapies for cardiovascular disease. Emory Department of Medicine Vice Chair and Cardiology Division Director W. Robert Taylor, MD, PhD; Rebecca Levit, MD; and Young-sup Yoon, MD, PhD discuss the regenerative medicine program at Emory University School of Medicine.

Research Team

Dr. Young-sup Yoon

Areas of Research

Highlighted Publications

Circulation. 2025

Circulation. 2023

Nature Biomedical Engineering. 2021

Nature Methods. 2019

Circulation Research. 2017

Circulation. 2017

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